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2006 NFL Draft Round 1
| 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 |
| Round 1 | Round 2 | Round 3 | Round 4 | Round 5 | Round 6 | Round 7 |
| Pick |
Team |
Player |
Position |
College |
| 1. | Houston Texans | Mario Williams | DE | North Carolina State |
| 2. | New Orleans Saints | Reggie Bush | RB | USC |
| 3. | Tennessee Titans | Vince Young | QB | Texas |
| 4. | New York Jets | D'Brickashaw Ferguson | OT | Virginia |
| 5. | Green Bay Packers | A.J. Hawk | OLB | Ohio State |
| 6. | San Francisco 49ers | Vernon Davis | TE | Maryland |
| 7. | Oakland Raiders | Michael Huff | S | Texas |
| 8. | Buffalo Bills | Donte Whitner | S | Ohio State |
| 9. | Detroit Lions | Ernie Sims | OLB | Florida State |
| 10. | Arizona Cardinals | Matt Leinart | QB | USC |
| 11. | Denver Broncos | Jay Cutler | QB | Vanderbilt |
| 12. | Baltimore Ravens | Haloti Ngata | DT | Oregon |
| 13. | Cleveland Browns | Kamerion Wimbley | OLB | Florida State |
| 14. | Philadelphia Eagles | Brodrick Bunkley | DT | Florida State |
| 15. | St Louis Rams | Tye Hill | CB | Clemson |
| 16. | Miami Dolphins | Jason Allen | CB | Tennessee |
| 17. | Minnesota Vikings | Chad Greenway | OLB | Iowa |
| 18. | Dallas Cowboys | Bobby Carpenter | OLB | Ohio State |
| 19. | San Diego Chargers | Antonio Cromartie | CB | Florida State |
| 20. | Kansas City Chiefs | Tamba Hali | DE | Penn State |
| 21. | New England Patriots | Laurence Maroney | RB | Minnesota |
| 22. | San Francisco 49ers | Manny Lawson | OLB | North Carolina State |
| 23. | Tampa Bay Buccaneers | Davin Joseph | OG | Oklahoma |
| 24. | Cincinnati Bengals | Johnathan Joseph | CB | South Carolina |
| 25. | Pittsburgh Steelers | Santonio Holmes | WR | Ohio State |
| 26. | Buffalo Bills | John McCargo | DT | North Carolina State |
| 27. | Carolina Panthers | DeAngelo Williams | RB | Memphis |
| 28. | Jacksonville Jaguars | Marcedes Lewis | TE | UCLA |
| 29. | New York Jets | Nick Mangold | C | Ohio State |
| 30. | Indianapolis Colts | Joseph Addai | RB | Louisiana State |
| 31. | Seattle Seahawks | Kelly Jennings | CB | Miami (Fla.) |
| 32. | New York Giants | Mathias Kiwanuka | DE | Boston College |
| | Round 1 | Round 2 | Round 3 | Round 4 | Round 5 | Round 6 | Round 7 |
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